Product Description
Semaglutide | 10mg
Researching Metabolic Regulation, Appetite Signaling, and Glucose Control
What It Does
Semaglutide is a GLP-1 receptor agonist being studied for its role in regulating appetite, glucose metabolism, and energy balance. It is a focus in research exploring satiety signaling, gastric emptying, and long-term metabolic control.
What Researchers Explore
- Appetite regulation and satiety signaling pathways
- Glucose homeostasis and insulin response
- Gastric emptying and digestive signaling
- Body weight regulation mechanisms
- Cardiometabolic risk factor pathways
- Long-term metabolic adaptation
Technical Background
Semaglutide is a 31-amino acid peptide analog of glucagon-like peptide-1 (GLP-1) with approximately 94% sequence homology to the native hormone. It includes an amino acid substitution at position 8 to resist enzymatic degradation by DPP-4, along with a lipid modification that promotes albumin binding and extends circulating half-life.
These structural features support prolonged receptor activation at the GLP-1 receptor (GLP-1R), influencing pathways involved in glucose regulation, appetite control, and energy balance.
Common Research Applications
- GLP-1 receptor signaling and pharmacology research
- DPP-4 resistance and peptide stability studies
- Glucose regulation and insulin signaling models
- Cardiometabolic parameter research
- Obesity and weight regulation studies
- Albumin binding and peptide half-life research
Product Properties
Purity: 99%+ HPLC
Form: Lyophilized Powder
Size: 10mg
Molecular Weight: 4,113.58 Da
Amino Acids: 31
Category: Metabolic / Mitochondrial Research
Frequently Studied Together
- Tirzepatide (dual incretin receptor research)
- Retatrutide (triple receptor metabolic research)
- Cagrilintide (amylin pathway research)