Product Description
PT-141 | 10mg
Researching Melanocortin Signaling and Neuroendocrine Function
What It Does
PT-141 is a synthetic peptide being studied for its activity on central melanocortin pathways involved in neuroendocrine signaling and behavioral response. It is a focus in research exploring receptor-mediated effects on motivation, autonomic regulation, and central nervous system signaling.
What Researchers Explore
- Melanocortin receptor signaling pathways
- Neuroendocrine regulation and CNS activity
- Behavioral and motivational signaling mechanisms
- Autonomic nervous system modulation
- Appetite and energy balance pathways
- Central receptor-mediated physiological responses
Technical Background
PT-141 (Bremelanotide) is a cyclic heptapeptide derived from alpha-melanocyte-stimulating hormone (alpha-MSH), with a molecular weight of approximately 1,025.2 Da. It functions as an agonist at melanocortin receptors MC1, MC3, MC4, and MC5, with primary activity at MC3R and MC4R within the central nervous system.
It is designed for enhanced stability and receptor binding through cyclization, contributing to a measurable half-life and sustained receptor interaction. These pathways are associated with multiple physiological processes including neuroendocrine signaling, autonomic regulation, and behavioral response.
Common Research Applications
- MC3R and MC4R signaling pathway research
- Melanocortin system physiology studies
- Alpha-MSH analog and structure-activity research
- Appetite regulation and energy homeostasis
- Autonomic nervous system modulation studies
- Cyclic peptide stability and receptor binding research
Product Properties
Purity: 99%+ HPLC
Form: Lyophilized Powder
Size: 10mg
Molecular Weight: 1,025.2 Da
Category: Neuroendocrine Research
Frequently Studied Together
- Kisspeptin (HPG axis and neuroendocrine research)
- Oxytocin (social behavior and signaling research)
- BPC-157 (tissue repair and regeneration research)