Product Description
MOTS-C | 40mg
Researching Metabolic Regulation, Energy Production, and Longevity
What It Does
MOTS-c is a mitochondrial-derived peptide being studied for its role in regulating metabolic function and cellular energy production. It is a focus in research exploring exercise-mimetic pathways, glucose utilization, and mechanisms involved in endurance and metabolic health.
What Researchers Explore
- Endurance and exercise capacity pathways
- Glucose uptake and metabolic efficiency
- Fat oxidation and energy utilization
- Activation of cellular energy pathways
- Muscle maintenance and aging-related decline
- Metabolic adaptation and resilience
Technical Background
MOTS-c (MRWQEMGYIFYPRKLR) is a 16-amino acid peptide encoded within the mitochondrial 12S rRNA gene. It functions as a signaling molecule involved in mitochondrial-nuclear communication and metabolic regulation.
Research indicates that MOTS-c levels increase in response to exercise, with translocation from the mitochondria to the nucleus, where it activates antioxidant response element genes through pathways including the folate-AICAR-AMPK axis. Preclinical studies have shown improvements in insulin sensitivity, reductions in body weight, and modulation of inflammatory responses.
Common Research Applications
- Exercise mimetic and metabolic adaptation research
- AMPK pathway activation and energy metabolism studies
- Insulin sensitivity and glucose regulation research
- Mitochondrial signaling and communication studies
- Age-related metabolic decline research
- Antioxidant response pathway activation
Product Properties
Purity: 99%+ HPLC
Form: Lyophilized Powder
Size: 40mg
Sequence: MRWQEMGYIFYPRKLR
Amino Acids: 16
Category: Metabolic / Mitochondrial Research
Frequently Studied Together
- 5-Amino-1MQ (metabolic and NAD+ research)