Product Description
Cerebroprotein Hydrolysate | 60mg
Researching Neurotrophic Signaling, Neuroprotection, and Cognitive Recovery
What It Does
Cerebroprotein hydrolysate is a porcine brain-derived mixture of low-molecular-weight neuropeptides and free amino acids being studied for its role in neurotrophic signaling and neuronal survival. It is a focus in research exploring neuroprotection, synaptic plasticity, and recovery of brain tissue following ischemic or traumatic injury.
What Researchers Explore
- Neurotrophic factor signaling (BDNF, NGF, GDNF, and CNTF pathways)
- Neuronal survival following ischemic injury
- Cognitive function and memory-related pathways
- Synaptic plasticity and neurogenesis
- Oxidative stress and glutamate excitotoxicity in neural tissue
- Neuroinflammation and microglial activation
Technical Background
Cerebroprotein hydrolysate (CAS 12656-61-0) is produced by controlled enzymatic hydrolysis of porcine brain proteins, yielding a standardized mixture of peptides under 10 kDa together with free amino acids. The peptide fraction is reported to contain fragments that structurally resemble endogenous neurotrophic factors, and it is the same class of preparation studied clinically since the mid-20th century under the name Cerebrolysin.
Research indicates it may engage TrkA, TrkB, and related neurotrophin receptor pathways, activate PI3K/Akt and MAPK/ERK signaling, reduce glutamate-induced excitotoxicity, stabilize calcium homeostasis, and upregulate antioxidant enzymes such as superoxide dismutase. Additional findings suggest support for neurogenesis and synaptogenesis, along with reduced pro-inflammatory cytokine release and microglial activation in models of brain injury.
Common Research Applications
- Ischemic stroke recovery models
- Traumatic brain injury research
- Alzheimer's disease and vascular dementia models
- Neurotrophic factor and receptor signaling studies
- Neurogenesis and synaptogenesis research
- Cognitive aging and neurodegeneration research
Product Properties
Purity: 99%+ HPLC
Form: Lyophilized Powder
Size: 60mg
Source: Porcine brain protein hydrolysate
Composition: Low-molecular-weight peptides (<10 kDa) and free amino acids
CAS: 12656-61-0
Category: Neuroprotection / Cognitive Research
Frequently Studied Together
- Semax (cognitive and neuropeptide research)
- Selank (anxiolytic and cognitive research)
- Pinealon (neuroprotective peptide research)
- DSIP (sleep regulation and recovery research)